SENIOR RESEARCHERS
André Wolff, Senior PhD
Professsional: Wolff graduated in 1987 in Medicine at the Catholic University Nijmegen and specialized subsequently in anaesthesiology at the Radboud University Nijmegen Medical Centre. From 1992 until 2000 he worked in the St Anna Hospital in Oss as anaesthesiologist and started to specialize in Pain Medicine. From 1996 until 2000 he was chairman of the multidisciplinary Regional Pain Centre in north-east Brabant. From 2000 until 2003 he worked as anaesthesiologist and consultant in Pain Medicine in the Bernhoven Hospital and was medical co-ordinator of the multidisciplinary Regional Pain Centre. Wolff introduced neuromodulation and epiduroscopy in Oss and from 1999 to 2003 he was the leader of a multidisciplinary transmural project on the prevention of chronic pain. In 2002 he combined his activities with a part time function as a consultant in Pain Medicine at the department for pain treatment at the University Medical Centre of Utrecht. In 2003 he switched to the Radboud University Nijmegen Medical Centre (department for Anaesthesiology) and continued also as consultant in Pain Medicine at its Pain Treatment Centre. In 2006 he became chef de clinique at the department for Anesthesiology.
Scientific: In 1986, Wolff was in North-Sulawesi, Indonesia, for a research program on the regional epidemiology of Hepatitis-B. From 1992 to 1995 he joined in studies on animals in the animal laboratory of the department for Anaesthesiology at the Radboud University Nijmegen. From 1995, Wolff worked also for the Pain Knowledge Centre Nijmegen and co-operated in various projects, such as pain classification, prevention of chronic pain and epiduroscopy. He performed the studies for his PhD thesis on Segmental Nerve Root Blocks in Patients with Chronic Radiating Low Back Pain in Oss. His special interests are chronic (low back) pain, prevention of chronic pain and invasive diagnostic and therapeutic procedures. He is author of a number of publications and he is lecturer at various national and international meetings and congresses. He also organized scientific symposia and meetings on pain and pain treatment and teached medical and para-medical professionals in pain management. In 2006 Wolff has become Head of the Pain Knowledge Centre Nijmegen.
Other: Wolff is member of various national and international scientific and professional societies on pain and anaesthesiology. He is board member of the Pain Chapter of the Dutch Society for Anesthesiology (NVAsP), the Dutch Chapter of the Internal Association for the Study of Pain (NVBP), representative in the Platform for Pain and Pain Management (SWVP), and board member of the National Working group and foundation LANSET (spinal endoscopic techniques). Wolff collaborated in national working groups with respect to guidelines on pain management (invasive techniques, chronic non-specific low back pain).
Harry van Goor, Senior PhD
Harry van Goor was born on April 18 1957. After graduating from medical school (University Hospital Groningen, the Netherlands in 1983), he worked as organ procurement and transplant officer in the Department of Surgery, University Hospital Groningen. Surgical training was done in the Sophia Hospital Zwolle (1986 – 1989) and the University Hospital Groningen (1989 – 1992). From 1992 to 1994 he did postgraduate training in Vascular Surgery. Since 1994 he is staff member of the Department of Surgery (G-I Surgery), University Medical Centre St Radboud in Nijmegen and was appointed Associate Professor in Surgery with a special assignment for surgical education in 1999.
At present he is vice-chairman of the surgical training programme, member of the medical student educational management team and bachelor/master implementation group.
Clinical Fields of Interest: Main interests are acute en chronic pancreatitis, benign and malignant biliary and pancreatic surgery, postsurgical adhesion formation, abdominal wall reconstructive surgery, surgical infection and peri-operative care (acute and chronic pain, in particular).
Scientific research: Scientific research is focused on pain in acute and chronic pancreatitis, chronification of pain after surgery, intra abdominal inflammation and infection and adhesion formation. The research is part of the research programme IV of the Research Institute of the University Medical Centre Nijmegen.
Scientific achievements: He authored more than 80 scientific papers and bookchapters.
General board activities: At present he is board member of the PAX (adhesion) society, board member of the Nijmegen Institute for Infectious Diseases, faculty member of the Gastro-Intestinal Workshop in Davos Switzerland, and member of the advisory board of the Dutch Pancreatitis Society (Nederlandse Alvleesklier Patienten Vereniging).
Jörgen Bruhn, Senior PhD
Postgraduate
1993-1995 Internship (Arzt im Praktikum), Department of Internal Medicine, DRK Hospital Bremerhaven (Chairman: Prof. Dr. U. Sander)
1994 Doctoral thesis (Characterization of the diastolic dysfunction in dilative cardiomyopathies: correlation of haemodynamic and echocardiographic data)
1995-1996 Resident, Department of Internal Medicine, DRK Hospital Bremerhaven (Chairman: Prof. Dr. U. Sander)
1996-1999 Resident, Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn (Chairman: Prof. Dr. A. Hoeft)
1999 6 month research fellowship, Stanford University, USA, Department of Anesthesia, Division of Clinical Pharmacology in Anesthesia(Chairman: S.L. Shafer, MD) as a fellow of the PAIRE (Palo Alto Institute of Research and Education), USA
1999-2001 Resident, Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn (Chairman: Prof. Dr. A. Hoeft)
Appointments and Positions
2001-March 2006 Faculty, Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn (Chairman: Prof. Dr. A. Hoeft)
April 2006-present Faculty, Department of Anaesthesiology, Universitair Medisch Centrum St. Radboud Nijmegen (Chairman: Prof. Dr. G.J. Scheffer)
February 2004 Leader of the anaesthesia team, Noma Medical AidMission Team 25, Sokoto, Nigeria
February 2006 Leader of the anaesthesia team, Noma Medical Aid Mission Team 33, Sokoto, Nigeria
Certification and Licensure
Speciality certification
1996 Board certification in Emergency Medical Aid
1998 Board certification in Chirotherapy
2001 Board certification in Acupuncture
2001 Board certification in Anaesthesiology
2004 Board certification in Intensive Care Medicine
2004 Advanced training course "Leitender Notarzt"
2005 Course "Spezielle Algesiologie" (Part Theory for the Board certification in Pain Medicine)
Medical licensure
University of Hamburg Medical School 1993 Free and Hanseatic city of Hamburg, Authority for labour, health and social welfare, Germany
Memberships in Professional and Scientific Societies
German Society of Anaesthesiology and Intensive Care Medicine
Association of German Anaesthesiologists
German Academy for Acupuncture and Auriculo-Medicine
Medical Association North Rhine
European Society of Anaesthesiologists
Scholarship
Scholarship of the PAIRE (Palo Alto Institute of Research and Education) for a 6 month research fellowship at the Department of Anesthesia, Division of Clinical Pharmacology in Anesthesia, Stanford University, USA
Habilitation/ PhD-Program
Habilitation at the University of Bonn (2003)
Habilitation-Thesis ("Entropy - a new approach to quantify the effects of anaesthetic drugs on the electroencephalogram")
Direction of Doctoral theses
A.Grzesiak: Bispectral index and A-line AAI index as guidance for desflurane-remifentanil anaesthesia compared with a standard practice group
V.M. Liermann: Spectral entropy and bispectral index as measures of the electroencephalographic effects of sevoflurane
T.M. Alves: Spectral entropy and bispectral index as measures of the EEG effects of propofol
G. Riese: Enhanced guidance of anaesthesia with EEG monitoring: comparing between bispectral index, spectral entropy and standard practice group
Organization of scientific meetings and workshops
1st workshop EEG-guided Anaesthesia, 20.-21. March 2003, Bonn
2nd workshop EEG-guided Anaesthesia, 13.-14. November 2003, Bonn
3rd workshop EEG-guided Anaesthesia, 12.-13. February 2004, Bonn
4th workshop EEG-guided Anaesthesia, 11.-12. November 2004, Bonn
Participation in the Program of scientific meetings in the past 5 years
German anaesthesia congress, 6.-9. May 2000, Munich
ASA (American Society of Anaesthesiologists) annual meeting 14.-18. October 2000, San Francisco
German anaesthesia congress, 13.-16. June 2001, Nuremberg
ESA (European Society of Anaesthesiologists) annual meeting 6.-9. April 2002, Nizza
German anaesthesia congress, 22.-25. June 2002, Nuremberg
ASA (American Society of Anaesthesiologists) annual meeting 12.-16. October 2002, Orlando
German anaesthesia congress, 9.-12. April 2003, Munich
ASA (American Society of Anaesthesiologists) annual meeting 11.-15. October 2003, San Francisco
German anaesthesia congress, 19.-22. June 2004, Nuremberg
ESA (European Society of Anaesthesiologists) annual meeting 5.-8. June 2004, Lissabon
ASA (American Society of Anaesthesiologists) annual meeting 23.-27. October 2004, Las Vegas
ASA (American Society of Anaesthesiologists) annual meeting 22.-26. October 2005, Atlanta
Westdeutsche Anästhesietage (WAT) 10.-12. March 2006, Bochum
EuroSIVA 1.-2. June 2006, Madrid
Reviewer for Medical Journals
Anaesthesiologie & Intensivmedizin [german]
Der Anaesthesist [german]
Journal of Clinical Monitoring and Computing
European Journal of Anaesthesiology
British Journal of Anaesthesia
Anaesthesiology
Member of the Editorial Board
Journal of Clinical Monitoring and Computing
Basic research
Mathematical analysis of electroencephalographic raw data
Pharmacokinetic simulations
Clinical research
Simultaneous pharmacokinetic-pharmacodynamic modeling
Pharmacodynamic interaction of nitrous oxide with halogenated volatile anaesthetics
Quantitation of anaesthetic drug effects on the EEG
Guidance of anaesthesia with neuromonitoring
Non-steady state analysis of pharmacokinetic interactions
Mixed effects modeling of the ventilatory depressant potency of anaesthetic drugs
Pharmacodynamic interaction and response surface modeling
Willem Brinkert, PhD candidate
Tobias Schreyer, MD, PhD candidate
Schreyer graduated in 1990 in Medicine at Medical High School, Hannover, Germany. He specialized subsequently in anaesthesiology at Medical High School Hannover.
Since 2000, he is working at Radboud University Nijmegen Medical Centre and is now specializing in Pain Medicine.
Scientific: Schreyer has worked with electroencephalogram to evaluate depth of anaesthesia. He is now working for the Pain Knowledge Centre Nijmegen and PNRG.
Monique Steegers, PhD candidate
